Injections into and around a joint

Injections can reduce symptoms in some conditions at some moments, but they are not a permanent fix, and the evidence differs by what is injected. This page sets out what each kind does.

On this page

Where injections sit

An injection is neither the first step nor the last. It is generally considered when activity change, rehabilitation and oral or topical medicine have not been enough, and when reducing symptoms for a while would let you get on with recovery.

That is the key point: an injection pays off most when you use the better weeks to do the rehabilitation. Spend them going back to full load instead, and the symptoms usually return.

A cross-section of the knee showing the bones, the cartilage surfaces and the space inside the joint, with a gloved hand passing a needle through the skin into that space
The needle passes through the skin into the joint space, not into the cartilage.Illustration: Assoc. Prof. Sorawut Thamyongkit, M.D.

What gets injected

Corticosteroid

The most commonly used. It reduces inflammation quickly, often within days, and is used in conditions such as frozen shoulder, trigger finger and osteoarthritis with an inflammatory component.

The limits are that the effect lasts weeks to months rather than permanently, and that repeating it too often is not good for the surrounding tissue — so doctors space injections out and cap the number. Anyone with diabetes should know that blood glucose can rise for a short period afterwards.

Hyaluronic acid

A systematic review and meta-analysis of 19 randomised trials with 1,629 patients, across rotator cuff disease, elbow pain, ankle sprains, Achilles and patellar tendinopathy and trigger finger, found benefit for pain in the short term and beyond 12 weeks compared with placebo and other comparators.

The reviewers also noted high heterogeneity between trials in some conditions, and uncertain benefit specifically for trigger finger, concluding that larger trials are needed to establish how it compares with other injectables.

Platelet-rich plasma (PRP)

Your own blood is spun down and re-injected. The evidence is inconsistent and varies considerably by condition and preparation method. It is often expensive and frequently not covered. If it is offered, ask directly how strong the evidence is for your particular problem.

During and after

The injection itself is quick. The skin is cleaned and local anaesthetic may be used; some sites are done under ultrasound guidance for accuracy.

Afterwards it can ache or feel tighter for a day or two before it improves. Doctors usually advise avoiding heavy use briefly, then starting the rehabilitation programme.

A clinician in scrubs and gloves injecting a patient’s knee as he lies back on a couch, with a bolster under the knee and a tray of equipment beside them
A joint injection is done in the clinic room and takes a few minutes.Illustration: Assoc. Prof. Sorawut Thamyongkit, M.D.

When to see a doctor

Three panels: resting with the leg up on a footstool under a wall clock, walking outdoors again, and a knee that is red, swollen and hot beside a thermometer and a hand reaching for a phone
Most of the days afterwards are simply rest. A joint turning swollen, red and hot is a different matter.Illustration: Assoc. Prof. Sorawut Thamyongkit, M.D.

Questions to ask your doctor

  • What exactly is being injected, and how long is it expected to last?
  • How good is the evidence for this injection in my condition?
  • How many can I have, and how far apart?
  • What should I do and avoid afterwards, and for how many days?
  • If it does not help, what is next?

Frequently asked questions

Can I have steroid injections often?

They should be spaced out and limited in number, because repeating them too frequently is not good for the tissue around the joint. Your doctor will set an interval that suits your case.

Will an injection cure it?

Most injections reduce symptoms for a while, to give you a window for rehabilitation and activity change. Used that way, the benefit usually lasts longer than the injection alone would.

Why do some doctors use ultrasound to guide the needle?

To see the needle tip while injecting and place the drug precisely — particularly for deeper joints, or where structures sit close together.

References

  1. Khan M et al. The Role of Hyaluronic Acid for Soft Tissue Indications: A Systematic Review and Meta-Analysis. Sports Health. 2022
  2. Leow MQH et al. Non-steroidal anti-inflammatory drugs (NSAIDs) for trigger finger. Cochrane Database Syst Rev. 2021

Related conditions

Written by Assoc. Prof. Sorawut Thamyongkit, M.D.